|
|
8,11,14-eicosatrienoic_acid + O2 + ferricytochrome_b5 + H+ <=> Arachidonoyl-CoA + H2O + ferricytochrome_b5
|
1.14.19.44
acyl-CoA (8-3)-desaturase
|
–
|
MK
|
|
BRENDA:
BR51508;
BS433635
KEGG:
R11059
MetaCyc:
RXN-16064
|
|
|
|
arachidonic_acid + CoA + ATP <=> Arachidonoyl-CoA + diphosphate + AMP
|
1.13.12.7
firefly luciferase
6.2.1.15
arachidonate---CoA ligase
6.2.1.2
medium-chain acyl-CoA ligase
6.2.1.3
long-chain-fatty-acid---CoA ligase
|
–
–
–
–
|
|
|
BRENDA:
BR66
KEGG:
R01598
MetaCyc:
ARACHIDONATE--COA-LIGASE-RXN
|
|
|
|
Arachidonoyl-CoA + lysophosphatidic_acid <=> 1-acyl-2-arachidonoyl-sn-glycerol_3-phosphate + CoA
|
2.3.1.51
1-acylglycerol-3-phosphate O-acyltransferase
|
–
|
|
|
BRENDA:
BS321026
MetaCyc:
RXN-20528
|
|
|
|
Arachidonoyl-CoA + H2O <=> CoA + arachidonic_acid
|
3.1.2.2
palmitoyl-CoA hydrolase
3.1.2.20
acyl-CoA hydrolase
3.1.2.25
phenylacetyl-CoA hydrolase
|
–
–
–
|
K
|
|
BRENDA:
BS360750
KEGG:
R08183
SABIO-RK:
6601
|
|
|
|
Arachidonoyl-CoA + glycine <=> CoA + arachidonoyl_glycine
|
2.3.1.13
glycine N-acyltransferase
2.3.1.65
bile acid-CoA:amino acid N-acyltransferase
|
–
–
|
|
|
BRENDA:
BS420304
SABIO-RK:
13310
|
|
|
|
Arachidonoyl-CoA + CDP-acylglycerol <=> CoA + CDP-diacylglycerol
|
not assigned
|
–
|
|
|
KEGG:
R01798
|
|
|
|
malonyl-CoA + Arachidonoyl-CoA + H+ <=> (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CoA + CO2
|
2.3.1
|
–
|
M
|
|
MetaCyc:
RXN-16079
|
- (4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)
- (4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)
|
|
|
Arachidonoyl-CoA + cholesterol <=> cholesteryl_arachidonate + CoA
|
2.3.1.26
sterol O-acyltransferase
|
–
|
|
|
MetaCyc:
RXN-20232
|
|
|
|
Arachidonoyl-CoA + sn-glycerol_3-phosphate <=> 1-arachidonoyl-lysophosphatidic_acid + CoA
|
2.3.1.15
glycerol-3-phosphate 1-O-acyltransferase
|
–
|
M
|
|
MetaCyc:
RXN-20513
|
|
|
|
Arachidonoyl-CoA + flavin <=> (2E,5Z,8Z,11Z,14Z)-2,5,8,11,14-eicosapentaenoyl-CoA + reduced_flavodoxin
|
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS396430
|
|
|
|
Arachidonoyl-CoA + dihydroxyacetone_phosphate <=> CoA + arachidonoyldihydroxyacetone_phosphate
|
2.3.1.42
glycerone-phosphate O-acyltransferase
|
–
|
|
|
BRENDA:
BS320897
|
|
|
|
Arachidonoyl-CoA + dihydroxyacetone_phosphate <=> CoA + arachidonoylglycerone_phosphate
|
2.3.1.42
glycerone-phosphate O-acyltransferase
|
–
|
|
|
BRENDA:
BS455318
|
|
|
|
Arachidonoyl-CoA + sn-glycerol_3-phosphate <=> CoA + 1-arachidonoyl-sn-glycerol_3-phosphate
|
2.3.1.15
glycerol-3-phosphate 1-O-acyltransferase
|
–
|
|
|
BRENDA:
BS320543
|
|
|
|
Arachidonoyl-CoA + lysophosphatidylcholine <=> CoA + 1-acyl-2-arachidonoyl-glycerophosphocholine
|
2.3.1.23
1-acylglycerophosphocholine O-acyltransferase
|
–
|
|
|
BRENDA:
BS320729
|
|
|
|
Arachidonoyl-CoA + lysophosphatidylcholine <=> CoA + 1-acyl-2-arachidonoyl-lysophosphatidylcholine
|
2.3.1.23
1-acylglycerophosphocholine O-acyltransferase
|
–
|
|
|
BRENDA:
BS454336
|
|
|
|
Arachidonoyl-CoA + NADPH + H+ <=> (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenal + CoA + NADP+
|
1.2.1.42
hexadecanal dehydrogenase (acylating)
1.2.1.50
long-chain acyl-protein thioester reductase
|
–
–
|
|
|
BRENDA:
BS424663
|
|
|
|
Arachidonoyl-CoA + NADPH <=> cis-5,8,11,14-eicosatetraenal + NADP+ + CoA
|
1.2.1.84
alcohol-forming fatty acyl-CoA reductase
|
–
|
|
|
BRENDA:
BS372423
|
|
|
|
Arachidonoyl-CoA + reduced_acceptor + O2 <=> 5,8,11,14,17-eicosadecapentaenoyl-CoA + acceptor + H2O
|
1.14.19.6
acyl-CoA (9+3)-desaturase
|
–
|
|
|
BRENDA:
BS395988
|
|
|
|
Arachidonoyl-CoA + diacylglycerol <=> CoA + 1,2-diacyl-3-arachidnoylglycerol
|
2.3.1.20
diacylglycerol O-acyltransferase
|
–
|
|
|
BRENDA:
BS455312
|
|
|
|
Arachidonoyl-CoA + diacylglycerol <=> CoA + 3-arachidonoyl-1,2-diacylglycerol
|
2.3.1.20
diacylglycerol O-acyltransferase
|
–
|
|
|
BRENDA:
BS320624
|
|
|
|
Arachidonoyl-CoA + 1-acylglycerophosphoinositol <=> CoA + 1-acyl-2-arachidonoyl-sn-glycero-3-phosphoinositol
|
2.3.1.23
1-acylglycerophosphocholine O-acyltransferase
|
–
|
|
|
BRENDA:
BS320726
|
|
|
|
Arachidonoyl-CoA + 1-stearoyl-sn-glycerol_3-phosphate <=> CoA + 1-stearoyl-2-arachidonoyl-sn-glycerol_3-phosphate
|
2.3.1.51
1-acylglycerol-3-phosphate O-acyltransferase
|
–
|
|
|
BRENDA:
BS408414
|
|
|
|
Arachidonoyl-CoA + 1-stearoyl-sn-glycerol_3-phosphate <=> CoA + 1-oleoyl-2-stearoyl-sn-glycerol_3-phosphate
|
2.3.1.51
1-acylglycerol-3-phosphate O-acyltransferase
|
–
|
|
|
BRENDA:
BS420303
|
|
|
|
Arachidonoyl-CoA + 2-arachidonoyl-sn-glycero-3-phosphocholine <=> CoA + 1-arachidonoyl-2-arachidonoyl-sn-glycero-3-phosphocholine
|
2.3.1.62
2-acylglycerophosphocholine O-acyltransferase
|
–
|
|
|
BRENDA:
BS321148
|
|
|
|
Arachidonoyl-CoA + hexadecanol <=> CoA + arachidonoyl_hexadecanate
|
2.3.1.75
long-chain-alcohol O-fatty-acyltransferase
|
–
|
|
|
BRENDA:
BS455320
|
|
|
|
Arachidonoyl-CoA + 1-palmitoyl-sn-glycerol_3-phosphate <=> CoA + 1-palmitoyl-2-arachidonoyl-sn-glycerol_3-phosphate
|
2.3.1.51
1-acylglycerol-3-phosphate O-acyltransferase
|
–
|
|
|
BRENDA:
BS420302
|
|
|
|
1,2-dioleoylglycerol + Arachidonoyl-CoA <=> 1,2-dioleoyl-3-arachidonoylglycerol + CoA
|
2.3.1.20
diacylglycerol O-acyltransferase
|
–
|
|
|
BRENDA:
BS419738
|
|
|
|
Arachidonoyl-CoA + lysophosphatidylcholine_18:1 <=> CoA + 1-oleoyl-2-arachidonoylphosphatidylcholine
|
2.3.1.51
1-acylglycerol-3-phosphate O-acyltransferase
|
–
|
|
|
BRENDA:
BS408411
|
|
|
|
Arachidonoyl-CoA + octopamine <=> CoA + N-arachidonoyloctopamine
|
2.3.1.87
aralkylamine N-acetyltransferase
|
–
|
|
|
BRENDA:
BS435337
|
|
|
|
DL-erythro-sphingosine + Arachidonoyl-CoA <=> N-arachidonoyl-DL-sphingosine + CoA
|
2.3.1.24
sphingosine N-acyltransferase
|
–
|
|
|
BRENDA:
BS449866
|
|
|
|
sphinganine + Arachidonoyl-CoA <=> N-arachidonoyl-DL-dihydrosphingosine + CoA
|
2.3.1.24
sphingosine N-acyltransferase
|
–
|
|
|
BRENDA:
BS450638
|
|
|
|
Arachidonoyl-CoA + dolichol <=> CoA + dolichyl_arachidonate
|
2.3.1.123
dolichol O-acyltransferase
|
–
|
|
|
BRENDA:
BS320393
|
|
|
|
Arachidonoyl-CoA + lysophosphatidylcholine_18:0 <=> CoA + 1-stearoyl-2-arachidonoyl-sn-glycerol_3-phosphocholine
|
2.3.1.51
1-acylglycerol-3-phosphate O-acyltransferase
|
–
|
|
|
BRENDA:
BS408415
|
|
|
|
1-palmitoyl-sn-glycero-3-phosphocholine + Arachidonoyl-CoA <=> CoA + 1-palmitoyl-2-arachidonoylphosphatidylcholine
|
2.3.1.23
1-acylglycerophosphocholine O-acyltransferase
2.3.1.51
1-acylglycerol-3-phosphate O-acyltransferase
|
–
–
|
|
|
BRENDA:
BS395278
|
|
|
|
Arachidonoyl-CoA + 1-acyl-sn-glycero-3-phosphoethanolamine <=> CoA + 1-acyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine
|
2.3.1.23
1-acylglycerophosphocholine O-acyltransferase
|
–
|
|
|
BRENDA:
BS320727
|
|
|
|
Arachidonoyl-CoA + 1-arachidonoyl-sn-glycerol_3-phosphate <=> CoA + 1,2-diarachidonoyl-sn-glycerol_3-phosphate
|
2.3.1.51
1-acylglycerol-3-phosphate O-acyltransferase
|
–
|
|
|
BRENDA:
BS420300
|
|
|
|
1-hexadecanoyl-glycero-3-phosphoethanolamine + Arachidonoyl-CoA <=> 1-palmitoyl-2-arachidonoylphosphatidylethanolamine + CoA
|
2.3.1.23
1-acylglycerophosphocholine O-acyltransferase
|
–
|
|
|
BRENDA:
BS407749
|
|
|
|
Arachidonoyl-CoA + 1-hexadecanoyl-glycero-3-phosphoethanolamine <=> CoA + 2-arachidonoyl-1-palmitoylphosphatidylethanolamine
|
2.3.1.23
1-acylglycerophosphocholine O-acyltransferase
|
–
|
|
|
BRENDA:
BS396428
|
|
|
|
Arachidonoyl-CoA + arachidonoyl_lysophosphatidylcholine <=> CoA + 2-arachidonoyl-1-arachidoylphosphatidylcholine
|
2.3.1.23
1-acylglycerophosphocholine O-acyltransferase
|
–
|
|
|
BRENDA:
BS396425
|
|
|
|
Arachidonoyl-CoA + 1-oleoyl-sn-glycerol_3-phosphate <=> CoA + 1-oleoyl-2-arachidonoyl-sn-glycerol_3-phosphate
|
2.3.1.51
1-acylglycerol-3-phosphate O-acyltransferase
|
–
|
|
|
BRENDA:
BS420301
|
|
|
|
Arachidonoyl-CoA + 1-oleoyl-sn-glycerol_3-phosphate <=> 1-oleoyl-2-arachidonoyl-glycerol-3-phosphate + CoA
|
2.3.1.51
1-acylglycerol-3-phosphate O-acyltransferase
|
–
|
|
|
BRENDA:
BS376305
|
|
|
|
1-palmitoyl-2-lysophosphatidylserine + Arachidonoyl-CoA <=> 1-palmitoyl-2-arachidonoylphosphatidylserine + CoA
|
2.3.1.23
1-acylglycerophosphocholine O-acyltransferase
|
–
|
|
|
BRENDA:
BS407751
|
|
|
|
Arachidonoyl-CoA + sn-2-monooleoylglycerol <=> CoA + 1-arachidonoyl-2-oleoylglycerol
|
2.3.1.22
2-acylglycerol O-acyltransferase
|
–
|
|
|
BRENDA:
BS320688
|
|
|
|
Arachidonoyl-CoA + 1-acyl-sn-glycero-3-phosphoserine <=> CoA + 1-acyl-2-arachidonoyl-sn-glycero-3-phosphoserine
|
2.3.1.23
1-acylglycerophosphocholine O-acyltransferase
|
–
|
|
|
BRENDA:
BS320728
|
|
|
|
Arachidonoyl-CoA + 1-alkyl-sn-glycero-3-phosphocholine <=> CoA + 2-arachidonoyl-1-alkyl-sn-glycero-3-phosphocholine
|
2.3.1.63
1-alkylglycerophosphocholine O-acyltransferase
|
–
|
|
|
BRENDA:
BS321159
|
|
|
|
Arachidonoyl-CoA + 2-acyl-sn-glycerol_3-phosphate <=> CoA + 1-arachidonoyl-2-acyl-sn-glycerol_3-phosphate
|
2.3.1.52
2-acylglycerol-3-phosphate O-acyltransferase
|
–
|
|
|
BRENDA:
BS321056
|
|
|
|
Arachidonoyl-CoA + 1-O-hexadecyl-sn-glycero-3-phosphocholine <=> CoA + 2-arachidonoyl-1-O-hexadecyl-sn-glycero-3-phosphocholine
|
2.3.1.23
1-acylglycerophosphocholine O-acyltransferase
|
–
|
|
|
BRENDA:
BS396426
|
|
|
|
Arachidonoyl-CoA + 1-oleoyl-2-lysophosphatidylcholine <=> CoA + 1-oleoyl-2-arachidonoylphosphatidylcholine
|
2.3.1.51
1-acylglycerol-3-phosphate O-acyltransferase
|
–
|
|
|
BRENDA:
BS408410
|
|
|
|
Arachidonoyl-CoA + 1-alkenylglycerophosphoethanolamine <=> CoA + 1-alkenyl-2-arachidonoylglycerophosphoethanolamine
|
2.3.1.121
1-alkenylglycerophosphoethanolamine O-acyltransferase
|
–
|
|
|
BRENDA:
BS320380
|
|
|
|
Arachidonoyl-CoA + 1-stearoyl-sn-glycero-3-phosphocholine <=> CoA + 1-stearoyl-2-arachidonoyl-lysophosphatidylcholine
|
2.3.1.23
1-acylglycerophosphocholine O-acyltransferase
|
–
|
|
|
BRENDA:
BS455316
|
|
|
|
Arachidonoyl-CoA + 1-stearoyl-sn-glycero-3-phosphocholine <=> CoA + 2-arachidonoyl-1-stearoylphosphatidylcholine
|
2.3.1.23
1-acylglycerophosphocholine O-acyltransferase
|
–
|
|
|
BRENDA:
BS396429
|
|
|
|
Arachidonoyl-CoA + NBD-labelled_lysophosphatidylcholine <=> CoA + NBD-2-arachidonoyl-phosphatidylcholine
|
2.3.1.23
1-acylglycerophosphocholine O-acyltransferase
|
–
|
|
|
BRENDA:
BS455321
|
|
|
|
Arachidonoyl-CoA + 1-acyl-lysophosphatidic_acid <=> CoA + 1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-lysophosphatidic_acid
|
2.3.1.51
1-acylglycerol-3-phosphate O-acyltransferase
|
–
|
|
|
BRENDA:
BS454749
|
|
|
|
Arachidonoyl-CoA + 1-acyl-lysophosphatidic_acid <=> CoA + 1-acyl-2-arachidonoyl-lysophosphatidic_acid
|
2.3.1.51
1-acylglycerol-3-phosphate O-acyltransferase
|
–
|
|
|
BRENDA:
BS455313
|
|
|
|
Arachidonoyl-CoA + 1-acyl-lysophosphatidylethanolamine <=> CoA + 1-acyl-2-arachidonoyl-lysophosphatidylethanolamine
|
2.3.1.23
1-acylglycerophosphocholine O-acyltransferase
|
–
|
|
|
BRENDA:
BS455314
|
|
|
|
Arachidonoyl-CoA + 1-acyl-lysophosphatidylinositol <=> CoA + 1-acyl-2-arachidonoyl-lysophosphatidylinositol
|
2.3.1.B46
|
–
|
|
|
BRENDA:
BS454337
|
|
|
|
Arachidonoyl-CoA + 1-acyl-lysophosphatidylserine <=> CoA + 1-acyl-2-arachidonoyl-lysophosphatidylserine
|
2.3.1.23
1-acylglycerophosphocholine O-acyltransferase
|
–
|
|
|
BRENDA:
BS455315
|
|
|
|
Arachidonoyl-CoA + 2-stearoyl-lysophosphatidylcholine <=> CoA + 1-arachidonoyl-2-stearoyl-lysophosphatidylcholine
|
2.3.1.23
1-acylglycerophosphocholine O-acyltransferase
|
–
|
|
|
BRENDA:
BS455317
|
|
|
|
Arachidonoyl-CoA + 2-Palmitoyl-sn-glycero-3-phosphocholine <=> CoA + 1-arachidonoyl-2-palmitoyl-sn-glycero-3-phosphocholine
|
2.3.1.62
2-acylglycerophosphocholine O-acyltransferase
|
–
|
|
|
BRENDA:
BS321147
|
|
|
|
Arachidonoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine <=> CoA + 1-alkenyl-2-arachidonoyl-glycero-3-phosphorylcholine
|
2.3.1.25
plasmalogen synthase
|
–
|
|
|
BRENDA:
BS320747
|
|
|
|
Arachidonoyl-CoA + 1-arachidonoyl-sn-lysophosphatidylcholine <=> CoA + 1-arachidonoyl-2-arachidonoyl-sn-glycero-3-phosphocholine
|
2.3.1.51
1-acylglycerol-3-phosphate O-acyltransferase
|
–
|
|
|
BRENDA:
BS408408
|
|
|
|
Arachidonoyl-CoA + 1-octadecenyl-2-lysophosphatidylinositol <=> CoA + 1-octadecenyl-2-arachidonoylphosphatidylinositol
|
2.3.1.51
1-acylglycerol-3-phosphate O-acyltransferase
|
–
|
|
|
BRENDA:
BS408409
|
|
|
|
Arachidonoyl-CoA + 1-palmitoyl-2-lysophosphatidylinositol <=> CoA + 1-palmitoyl-2-arachidonoylphosphatidylinositol
|
2.3.1.51
1-acylglycerol-3-phosphate O-acyltransferase
|
–
|
|
|
BRENDA:
BS408412
|
|
|
|
Arachidonoyl-CoA + phenazine_methosulfate <=> (2E,5Z,8Z,11Z,14Z)-2,5,8,11,14-eicosapentaenoyl-CoA + reduced_phenazine_methosulfate
|
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BS260375
|
|
|
|
1-palmitoyl-sn-glycero-3-phosphocholine + Arachidonoyl-CoA <=> CoA + 1-palmitoyl-2-arachidonyl-sn-glycero-3-phosphocholine
|
2.3.1.23
1-acylglycerophosphocholine O-acyltransferase
|
–
|
|
|
SABIO-RK:
12160
|
|